Simon Dardashti, MDPain Medicine Physician

Conditions Evaluated

Complex Regional Pain
Syndrome Evaluation.

Complex regional pain syndrome (CRPS) is a chronic pain condition that requires careful clinical evaluation. Diagnosis is based on accepted criteria interpreted in the context of the patient's history, symptoms, and physical examination.

In Brief

Complex Presentation

CRPS involves a constellation of findings that may include pain, sensory changes, autonomic dysregulation, and motor or trophic changes. No single finding confirms the diagnosis.

Diagnostic Criteria

Accepted diagnostic criteria describe features that must be present for a clinical diagnosis of CRPS. These criteria require careful clinical interpretation alongside the patient's history and examination.

Individualized Treatment

Treatment planning for CRPS depends on clinical presentation, functional goals, and prior treatment response. Options may include physical therapy, medication management, and selected interventional approaches.

Overview

What Is Complex Regional Pain Syndrome?

Complex regional pain syndrome (CRPS) is a chronic pain condition characterized by pain that is disproportionate to the inciting event or ongoing tissue injury, along with associated sensory, autonomic, and potentially motor and trophic changes. CRPS typically involves an extremity, though presentations vary in character and severity.

Two types are described: CRPS Type I, in which there is no confirmed nerve injury, and CRPS Type II, in which a specific nerve injury is identified. The distinction is based on clinical history and evaluation rather than imaging alone.

CRPS is a clinical diagnosis. It requires careful evaluation to support, and other conditions that may produce similar symptoms — including other nerve disorders, vascular conditions, or musculoskeletal pathology — must be considered as part of the diagnostic process.

Diagnosis

How CRPS Is Evaluated.

The diagnosis of CRPS is based on clinical findings rather than a single laboratory test or imaging study. Accepted diagnostic criteria — commonly the Budapest Criteria — describe a set of symptoms and signs that must be present and cannot be better explained by another diagnosis. Features that may be evaluated include:

  • Sensory changes — allodynia, hyperalgesia, or other sensory abnormalities
  • Vasomotor changes — skin temperature asymmetry or skin color changes
  • Sudomotor and edema findings — swelling or sweating abnormalities
  • Motor and trophic changes — weakness, tremor, dystonia, or changes to skin, hair, or nails

These findings must be interpreted in clinical context. Not all features are present in every patient, and findings may change over time or with treatment. Pain alone is not sufficient to support a diagnosis of CRPS.

Approach

How Dr. Dardashti Evaluates CRPS.

Evaluation includes a detailed history of symptom onset, character, location, and progression, along with review of relevant prior records, imaging, and treatments. Physical examination focuses on identifying features consistent with accepted diagnostic criteria while considering alternative or contributing diagnoses.

The clinical history — including the timing of symptom onset relative to any inciting event, the pattern of symptom evolution, prior treatments and their responses, and the patient's functional limitations — is an essential component of evaluation. The goal is a complete clinical picture, not a symptom checklist.

Treatment

Treatment Options That May Be Considered.

Treatment for CRPS is individualized based on clinical presentation and functional goals. Options that may be considered include:

  • Physical and occupational therapy coordination
  • Medication management when clinically appropriate
  • Selected nerve blocks or other procedures when clinically indicated
  • Spinal cord stimulation evaluation for selected patients with refractory symptoms
  • Ongoing reassessment based on treatment response and clinical findings

Treatment recommendations for CRPS are based on individual clinical evaluation and functional goals. Response to treatment varies among patients.

Limitations

Important Limitations.

CRPS is a complex condition that requires careful clinical evaluation. Diagnosis requires interpretation of findings in the context of accepted criteria and cannot be made from symptoms or imaging alone. Other conditions may produce similar findings. Treatment response varies and is not predictable in advance. A formal clinical evaluation is required for any individual patient. This page is for general informational purposes only and does not constitute medical advice or create a physician-patient relationship.

Dr. Dardashti sees patients in Mission Hills, California, serving patients from the San Fernando Valley, Santa Clarita Valley, and surrounding Los Angeles communities.